Here are my suggested settings for the my.cnf file. This should work well for a VPS with 256-512MB RAM.
Code:
[mysqld]
max_connections = 400
key_buffer = 16M
myisam_sort_buffer_size = 32M
join_buffer_size = 1M
read_buffer_size = 1M
sort_buffer_size = 2M
table_cache = 1024
thread_cache_size = 286
interactive_timeout = 25
wait_timeout = 1000
connect_timeout = 10
max_allowed_packet = 16M
max_connect_errors = 10
query_cache_limit = 1M
query_cache_size = 16M
query_cache_type = 1
tmp_table_size = 16M
skip-innodb
[mysqld_safe]
open_files_limit = 8192
[mysqldump]
quick
max_allowed_packet [...]
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